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OCR: ated with the The mineralocorticoid excess one (the rhetinic acid - ingestion of liquorice or carb hemisuccinate derivative of was once the active component of liqu of either of these believed to result as a direct e s now known agents on the kidney; howev condition is due 3-hydroxysteroid that this is not the case and t tisol to cortisone, to the inhibition of the enzy dehydrogenase which conve This enzyme plays a critical r as the kidney) in aldosterone-selective tissues ccess to the preventing cortisol from gain ptor. If it is non-specific mineralocortico en the so-called inhibited or congenitally abs ticoid excess syndrome of apparent miner ensues. See also: · Steroid Hormone Synthesi